Creamy Buffalo Chicken Alfredo Penne

Featured in Sophisticated Dinners Ready in 45 Minutes or Less.

Boil penne, stir together a creamy buffalo Alfredo sauce, toss with chicken and cheeses, and it's done in 30 minutes. Perfectly satisfying and spicy for busy nights.
Sarah
Updated on Fri, 14 Mar 2025 14:10:56 GMT
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Creamy Buffalo Chicken Alfredo Penne | chefmiarecipes.com

Experience a luxurious twist on classic pasta with this Buffalo Chicken Alfredo Penne. This creative dish combines smooth, creamy Alfredo sauce with zesty buffalo chicken for a memorable meal. The tender penne pasta, juicy shredded chicken, and rich cheese sauce work together perfectly, making every bite irresistible.

As a family favorite, this recipe consistently delivers outstanding results. The combination of flavors appeals to even those who typically avoid spicy foods, making it a reliable choice for gatherings.

Key Ingredients

  • Penne Pasta: Ridged pasta works best for maximum sauce adhesion
  • Heavy Cream: The essential base for a silky smooth sauce
  • Buffalo Sauce: Frank's RedHot recommended for optimal flavor
  • Parmesan and Mozzarella: Freshly grated for best melting properties
  • Chicken: Rotisserie or poached breast meat work equally well

Preparation Method

Cook Pasta:
Boil penne in salted water until al dente, approximately 11 minutes
Prepare Sauce Base:
Melt butter, sauté garlic until fragrant, about 1 minute
Make Sauce:
Add cream while whisking, incorporate buffalo sauce and seasonings until thickened
Add Cheese:
Gradually stir in cheeses until completely melted and smooth
Combine:
Mix in chicken and pasta until thoroughly coated with sauce
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Buffalo Chicken Alfredo Penne Recipe | chefmiarecipes.com

The buffalo sauce component adds the perfect level of heat while complementing the creamy base. Frank's RedHot Buffalo sauce consistently produces excellent results in this recipe.

Serving Suggestions

Serve with crispy garlic bread and fresh Caesar salad. Roasted vegetables like Brussels sprouts or asparagus make excellent side dishes.

Recipe Variations

Try substituting shrimp for chicken or adding sautéed mushrooms. For a lighter version, half-and-half can replace heavy cream.

Storage Instructions

Store leftovers in an airtight container up to three days. Reheat gently with a splash of cream, stirring occasionally.

This Buffalo Chicken Alfredo Penne combines classic comfort with bold flavors. Its straightforward preparation and reliable results make it a standout recipe for any occasion.

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Frequently Asked Questions

→ How spicy is this recipe?
It’s got a nice kick, but you can easily adjust by adding less buffalo sauce or more if you like it hot!
→ Does rotisserie chicken work here?
Absolutely, it’s a time-saver. Just shred and toss it into the sauce when you’re ready.
→ What can I pair with this pasta?
Try a crisp green salad or roasted veggies to lighten up the richness of the dish.
→ Can this pasta be vegetarian?
Definitely. Swap out chicken for sautéed mushrooms or your go-to meat substitute.
→ What’s the best way to reheat it?
Warm it gently on the stove or pop it in the microwave. Adding a splash of milk can bring the sauce back to life if it feels too thick.

Spicy Alfredo Chicken

A bold twist on Alfredo with hot buffalo sauce, juicy chicken, melty cheeses, and penne pasta.

Prep Time
10 Minutes
Cook Time
20 Minutes
Total Time
30 Minutes

Category: Weeknight Elegance

Difficulty: Easy

Cuisine: Italian-American Inspired Dish

Yield: 6 Servings

Dietary: ~

Ingredients

→ Cheese & Spices

01 1 teaspoon of Italian seasoning mix
02 A cup of grated Parmesan cheese
03 Half a cup of mozzarella, shredded
04 Salt and black pepper to your liking

→ Base for Sauce

05 Half a cup of buffalo-style hot sauce
06 Two garlic cloves, finely chopped
07 Two cups of thick, heavy cream
08 A quarter cup of butter

→ Pasta & Meat

09 One pound of penne pasta
10 Two cups of chicken, cooked and pulled apart

Instructions

Step 01

Get a big pot of water boiling, add salt to it. Cook the penne until it's just right (al dente) by checking the package's directions. Drain and leave it aside.

Step 02

Over medium heat, melt the butter in a large pan. Toss in the minced garlic and cook until aromatic. Then pour in the heavy cream, buffalo sauce, and seasoning mix. Let it simmer for about 5-7 minutes.

Step 03

While stirring, slowly add the Parmesan and mozzarella until they’re melted and make the sauce smooth and creamy.

Step 04

Put in the cooked chicken and penne. Stir until every bit of pasta and chicken is coated evenly in the creamy sauce.

Notes

  1. If you like it spicier, add more buffalo sauce.
  2. You can use a variety of cheeses to change things up.
  3. Swap the chicken for mushrooms if you'd like a veggie-friendly dish.

Tools You'll Need

  • Big pot
  • Skillet, large enough for mixing
  • Pasta strainer or colander

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Has dairy products (butter, cream, cheese)
  • Contains wheat-based pasta

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 510
  • Total Fat: ~
  • Total Carbohydrate: ~
  • Protein: ~